SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04796

Signal sequence   MKTALPLLLLTCLVAAVQS

Length  19

Organism  Aplysia californica (California sea hare)

UniProt ID  Q8I817,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04796.cif

Structure  SPKB04796.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1985.51454

Aliphatic index  169.4736842

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  708.13

Aromaticity  0

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -3.8895

Hydropathy 



Literature Information


Title  Recombinant production and structural studies of the Aplysia water-borne protein pheromone enticin indicates it has a novel disulfide stabilized fold.

DOI  10.1016/j.peptides.2006.08.027,

Publication Year  2007

PubMed ID  17141371,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.