SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04794

Signal sequence   MAKRPLLLLLLAVWVLAGELWLRTEA

Length  26

Organism  Sus scrofa (Pig)

UniProt ID  Q8HY17,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04794.cif

Structure  SPKB04794.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2976.70304

Aliphatic index  172.6923077

Isoelectric point  9.690164215

Charge (pH=7)   1.001232888

Topological polar surface area  1058.26

Aromaticity  0.076923077

Average rotatable bonds  3.692307692

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  34

X logP energy  -0.57056

Hydropathy 



Literature Information


Title  Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.

DOI  10.1074/jbc.M308995200,

Publication Year  2003

PubMed ID  14522968,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.