SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04788

Signal sequence   MGQFIFVSFGFLVVATSLSGTEA

Length  23

Organism  Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)

UniProt ID  Q8AV98,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04788.cif

Structure  SPKB04788.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2408.79454

Aliphatic index  97.39130435

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  885.06

Aromaticity  0.173913043

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -7.3031

Hydropathy 



Literature Information


Title  Molecular cloning of glycoprotein Ib-binding protein, flavocetin-A, which inhibits platelet aggregation.

DOI  10.1016/s0049-3848(00)00234-6,

Publication Year  2000

PubMed ID  10942790,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.