SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04787

Signal sequence   MERLIFVSFGLLVVILSLSGTGA

Length  23

Organism  Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)

UniProt ID  Q8AV97,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04787.cif

Structure  SPKB04787.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2422.95184

Aliphatic index  160.8695652

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  883.64

Aromaticity  0.086956522

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  -5.00703

Hydropathy 



Literature Information


Title  Molecular cloning of glycoprotein Ib-binding protein, flavocetin-A, which inhibits platelet aggregation.

DOI  10.1016/s0049-3848(00)00234-6,

Publication Year  2000

PubMed ID  10942790,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.