General Information
SPKB ID SPKB04784
Signal sequence MKFSSIILLTLLICSMSIFGNC
Length 22
Organism Androctonus australis (Sahara scorpion)
UniProt ID Q867F4,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04784.cif
Physicochemical Information
Molecular weight 2435.05414
Aliphatic index 141.8181818
Isoelectric point 8.229691165
Charge (pH=7) 0.873739834
Topological polar surface area 844.68
Aromaticity 0.090909091
Average rotatable bonds 3.727272727
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 34
X logP energy -5.2151
Hydropathy
Literature Information
Title Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom.
DOI 10.1016/s0005-2736(00)00259-5,
Publication Year 2000
PubMed ID 11018665,
Patent ID NA,