SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04784

Signal sequence   MKFSSIILLTLLICSMSIFGNC

Length  22

Organism  Androctonus australis (Sahara scorpion)

UniProt ID  Q867F4,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04784.cif

Structure  SPKB04784.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2435.05414

Aliphatic index  141.8181818

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  844.68

Aromaticity  0.090909091

Average rotatable bonds  3.727272727

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -5.2151

Hydropathy 



Literature Information


Title  Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom.

DOI  10.1016/s0005-2736(00)00259-5,

Publication Year  2000

PubMed ID  11018665,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.