SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04780

Signal sequence   MRSLLQFLALSAAIALCVC

Length  19

Organism  Argyrosomus regius (Meagre)

UniProt ID  Q800Y2,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04780.cif

Structure  SPKB04780.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2023.54084

Aliphatic index  159.4736842

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  732.57

Aromaticity  0.052631579

Average rotatable bonds  3.473684211

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -4.49433

Hydropathy 



Literature Information


Title  Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.

DOI  10.1359/jbmr.2003.18.2.244,

Publication Year  2003

PubMed ID  12568402,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.