SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04779

Signal sequence   MKQFLVVLLILSFVHG

Length  16

Organism  Aquarana catesbeiana (American bullfrog) (Rana catesbeiana)

UniProt ID  Q800A0,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04779.cif

Structure  SPKB04779.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1844.33184

Aliphatic index  176.25

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  617.84

Aromaticity  0.125

Average rotatable bonds  3.8125

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  22

X logP energy  0.0913

Hydropathy 



Literature Information


Title  Molecular cloning of preprocathepsin E cDNA from the stomach of bullfrog Rana catesbeiana.

DOI  10.1016/s1096-4959(03)00142-8,

Publication Year  2003

PubMed ID  12892756,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.