SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04778

Signal sequence   MIAFIVLLSLAAVLQQSSG

Length  19

Organism  Naja atra (Chinese cobra)

UniProt ID  Q7ZZN8,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04778.cif

Structure  SPKB04778.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1961.39034

Aliphatic index  169.4736842

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  733.99

Aromaticity  0.052631579

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -5.0919

Hydropathy 



Literature Information


Title  Purification and cloning of cysteine-rich proteins from Trimeresurus jerdonii and Naja atra venoms.

DOI  10.1016/s0041-0101(03)00234-4,

Publication Year  2003

PubMed ID  14529736,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.