SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04777

Signal sequence   MIAFIVLPILAAVLQQSSG

Length  19

Organism  Crotalus atrox (Western diamondback rattlesnake)

UniProt ID  Q7ZT99,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04777.cif

Structure  SPKB04777.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1971.42884

Aliphatic index  169.4736842

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  704.97

Aromaticity  0.052631579

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -3.578

Hydropathy 



Literature Information


Title  Wide distribution of cysteine-rich secretory proteins in snake venoms: isolation and cloning of novel snake venom cysteine-rich secretory proteins.

DOI  10.1016/s0003-9861(03)00028-6,

Publication Year  2003

PubMed ID  12646276,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.