SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04776

Signal sequence   MMFRLTSVSCFLLVIACLNLFQVVLT

Length  26

Organism  Conus virgo (Virgin cone)

UniProt ID  Q7YZS9,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04776.cif

Structure  SPKB04776.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2962.72144

Aliphatic index  153.4615385

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  1019.82

Aromaticity  0.115384615

Average rotatable bonds  3.692307692

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  38

X logP energy  -4.27083

Hydropathy 



Literature Information


Title  A novel conotoxin inhibiting vertebrate voltage-sensitive potassium channels.

DOI  10.1016/s0041-0101(03)00099-0,

Publication Year  2003

PubMed ID  12893060,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.