General Information
SPKB ID SPKB04775
Signal sequence MGRFISVSFGLLVVFLSLSGTGA
Length 23
Organism Echis multisquamatus (Central Asian sand viper)
UniProt ID Q7T2Q1,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04775.cif
Physicochemical Information
Molecular weight 2358.82424
Aliphatic index 126.9565217
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 866.57
Aromaticity 0.130434783
Average rotatable bonds 3.304347826
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 31
X logP energy -7.09763
Hydropathy
Literature Information
Title Isolation and characterization of EMS16, a C-lectin type protein from Echis multisquamatus venom, a potent and selective inhibitor of the alpha2beta1 integrin.
DOI 10.1021/bi000428a,
Publication Year 2000
PubMed ID 10933804,
Patent ID NA,