SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04775

Signal sequence   MGRFISVSFGLLVVFLSLSGTGA

Length  23

Organism  Echis multisquamatus (Central Asian sand viper)

UniProt ID  Q7T2Q1,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04775.cif

Structure  SPKB04775.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2358.82424

Aliphatic index  126.9565217

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  866.57

Aromaticity  0.130434783

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  -7.09763

Hydropathy 



Literature Information


Title  Isolation and characterization of EMS16, a C-lectin type protein from Echis multisquamatus venom, a potent and selective inhibitor of the alpha2beta1 integrin.

DOI  10.1021/bi000428a,

Publication Year  2000

PubMed ID  10933804,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.