General Information
SPKB ID SPKB04774
Signal sequence MGRLISVRFSLLVVFLSLSGIGAGLC
Length 26
Organism Echis multisquamatus (Central Asian sand viper)
UniProt ID Q7T2Q0,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04774.cif
Physicochemical Information
Molecular weight 2709.34704
Aliphatic index 157.3076923
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 995.54
Aromaticity 0.076923077
Average rotatable bonds 3.461538462
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 35
X logP energy -6.93536
Hydropathy
Literature Information
Title Isolation and characterization of EMS16, a C-lectin type protein from Echis multisquamatus venom, a potent and selective inhibitor of the alpha2beta1 integrin.
DOI 10.1021/bi000428a,
Publication Year 2000
PubMed ID 10933804,
Patent ID NA,