SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04773

Signal sequence   MIAFSLLCFAAVLQQSFG

Length  18

Organism  Naja atra (Chinese cobra)

UniProt ID  Q7T1K6,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04773.cif

Structure  SPKB04773.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1946.35274

Aliphatic index  119.4444444

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  684.66

Aromaticity  0.166666667

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -3.902

Hydropathy 



Literature Information


Title  Purification and cloning of cysteine-rich proteins from Trimeresurus jerdonii and Naja atra venoms.

DOI  10.1016/s0041-0101(03)00234-4,

Publication Year  2003

PubMed ID  14529736,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.