SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04768

Signal sequence   MRLIAALLSVLLIASTAQSTVTIYE

Length  25

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  Q7M438,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04768.cif

Structure  SPKB04768.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2678.22304

Aliphatic index  164

Isoelectric point  6.403313374

Charge (pH=7)   -0.001094303

Topological polar surface area  1045.62

Aromaticity  0.04

Average rotatable bonds  3.52

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -7.99183

Hydropathy 



Literature Information


Title  Characterization and primary structure of a base non-specific and acid ribonuclease from Dictyostelium discoideum.

DOI  10.1093/oxfordjournals.jbchem.a022189,

Publication Year  1998

PubMed ID  9756633,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.