SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04764

Signal sequence   MNKVYSLKYCPVTGGLIAVSELARRVIKKTCRRLTHILLAGIPAICLCYSQISQA

Length  55

Organism  Escherichia coli O44:H18 (strain 042 / EAEC)

UniProt ID  Q7BS42,

Motif  1..55



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell surface

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04764.cif

Structure  SPKB04764.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6065.37304

Aliphatic index  122.3636364

Isoelectric point  10.08424201

Charge (pH=7)   6.839025026

Topological polar surface area  2366.37

Aromaticity  0.054545455

Average rotatable bonds  3.672727273

Number of hydrogen bond donors  89

Number of hydrogen bond acceptors  84

X logP energy  -19.95822

Hydropathy 



Literature Information


Title  Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli.

DOI  10.1128/IAI.67.11.5587-5596.1999,

Publication Year  1999

PubMed ID  10531204,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.