SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04763

Signal sequence   MLKKAMVAAAAAASVIGMSAAAAPQALA

Length  28

Organism  Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

UniProt ID  Q7AY50,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04763.cif

Structure  SPKB04763.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2586.16474

Aliphatic index  108.9285714

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  975.82

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  37

X logP energy  -9.8981

Hydropathy 



Literature Information


Title  Two novel homologous proteins of Streptomyces coelicolor and Streptomyces lividans are involved in the formation of the rodlet layer and mediate attachment to a hydrophobic surface.

DOI  10.1046/j.1365-2958.2002.02980.x,

Publication Year  2002

PubMed ID  12067338,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.