SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04758

Signal sequence   MKRNILALVVVVALISQSRPAES

Length  23

Organism  Monoplex parthenopeus (Giant triton) (Monoplex echo)

UniProt ID  Q76CA2,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04758.cif

Structure  SPKB04758.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2495.02204

Aliphatic index  148.2608696

Isoelectric point  11.47969967

Charge (pH=7)   1.999457766

Topological polar surface area  1028.72

Aromaticity  0

Average rotatable bonds  3.652173913

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  34

X logP energy  -9.12446

Hydropathy 



Literature Information


Title  Primary structure of echotoxin 2, an actinoporin-like hemolytic toxin from the salivary gland of the marine gastropod Monoplex echo.

DOI  10.1016/s0041-0101(03)00226-5,

Publication Year  2003

PubMed ID  14529730,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.