SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04757

Signal sequence   MPSSVIMFTFLALTVLTAVMVGTSEA

Length  26

Organism  Acanthaster planci (Crown-of-thorns starfish)

UniProt ID  Q75WF2,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04757.cif

Structure  SPKB04757.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2717.28974

Aliphatic index  116.1538462

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  960.94

Aromaticity  0.076923077

Average rotatable bonds  3.269230769

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  38

X logP energy  -7.3664

Hydropathy 



Literature Information


Title  Plancitoxins, lethal factors from the crown-of-thorns starfish Acanthaster planci, are deoxyribonucleases II.

DOI  10.1016/j.toxicon.2004.06.012,

Publication Year  2004

PubMed ID  15450924,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.