SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04751

Signal sequence   MQQRGAAGSRGCALFPLLGVLFFQGVYIVFS

Length  31

Organism  Homo sapiens (Human)

UniProt ID  Q6UWV2,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04751.cif

Structure  SPKB04751.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3333.95994

Aliphatic index  100.6451613

Isoelectric point  9.49995979

Charge (pH=7)   1.935152547

Topological polar surface area  1241.29

Aromaticity  0.161290323

Average rotatable bonds  3.419354839

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  42

X logP energy  -9.22666

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.