SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04750

Signal sequence   MKPVWVATLLWMLLLVPRLGA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  Q6UWM7,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04750.cif

Structure  SPKB04750.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2408.09064

Aliphatic index  162.3809524

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  767.47

Aromaticity  0.095238095

Average rotatable bonds  3.476190476

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  1.74977

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.