SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04744

Signal sequence   MGRFIFVSFGLLVVFLSLSGAKG

Length  23

Organism  Bothrops insularis (Golden lancehead) (Lachesis insularis)

UniProt ID  Q6QX33,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3BX4,

Predicted Structure ID  SPKB04744.cif

Structure  SPKB04744.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2445.99164

Aliphatic index  126.9565217

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  852.13

Aromaticity  0.173913043

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -4.09903

Hydropathy 



Literature Information


Title  Cloning, characterization, and structural analysis of a C-type lectin from Bothrops insularis (BiL) venom.

DOI  10.1016/j.abb.2004.08.018,

Publication Year  2004

PubMed ID  15519291,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.