SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04735

Signal sequence   MGRSISVSFGLLAVFLSLSGTGA

Length  23

Organism  Macrovipera lebetinus (Levantine viper) (Vipera lebetina)

UniProt ID  Q696W1,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04735.cif

Structure  SPKB04735.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2270.67204

Aliphatic index  118.6956522

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  886.8

Aromaticity  0.086956522

Average rotatable bonds  3.217391304

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -9.98413

Hydropathy 



Literature Information


Title  Factor X activator from Vipera lebetina venom is synthesized from different genes.

DOI  10.1016/j.bbapap.2004.07.007,

Publication Year  2004

PubMed ID  15450849,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.