SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04734

Signal sequence   MCLPSCLLSIWVLFMAAQSLG

Length  21

Organism  Rattus norvegicus (Rat)

UniProt ID  Q63191,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04734.cif

Structure  SPKB04734.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2283.84834

Aliphatic index  134.7619048

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  756.1

Aromaticity  0.095238095

Average rotatable bonds  3.380952381

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -3.2208

Hydropathy 



Literature Information


Title  Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells.

DOI  10.1074/jbc.270.4.1583,

Publication Year  1995

PubMed ID  7829488,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.