SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04733

Signal sequence   MCLRSLFLVSLATCVVCG

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  Q63010,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04733.cif

Structure  SPKB04733.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1915.41594

Aliphatic index  140.5555556

Isoelectric point  8.04679067

Charge (pH=7)   0.81205684

Topological polar surface area  680.61

Aromaticity  0.055555556

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -5.14253

Hydropathy 



Literature Information


Title  Molecular aspects of carboxylesterase isoforms in comparison with other esterases.

DOI  10.1016/0378-4274(95)03493-5,

Publication Year  1995

PubMed ID  8597091,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.