SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04731

Signal sequence   MWKRWLALALVTIALVHG

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  Q62632,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04731.cif

Structure  SPKB04731.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2078.59254

Aliphatic index  157.2222222

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  726.43

Aromaticity  0.111111111

Average rotatable bonds  3.611111111

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  24

X logP energy  -0.18653

Hydropathy 



Literature Information


Title  Characterization of a rat C6 glioma-secreted follistatin-related protein (FRP). Cloning and sequence of the human homologue.

DOI  10.1111/j.1432-1033.1994.0937b.x,

Publication Year  1994

PubMed ID  7957230,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.