SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04729

Signal sequence   MAASALAWLLLWAAGLVGRLAA

Length  22

Organism  Rattus norvegicus (Rat)

UniProt ID  Q60GF7,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04729.cif

Structure  SPKB04729.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2225.72314

Aliphatic index  155.9090909

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  788.13

Aromaticity  0.090909091

Average rotatable bonds  3.090909091

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  26

X logP energy  -2.60963

Hydropathy 



Literature Information


Title  Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I.

DOI  10.1091/mbc.e04-09-0802,

Publication Year  2005

PubMed ID  15635094,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.