SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04728

Signal sequence   MRTGRVTPGLAAGLLLLLLRSFGLVEP

Length  27

Organism  Mus musculus (Mouse)

UniProt ID  Q60767,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04728.cif

Structure  SPKB04728.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2851.48984

Aliphatic index  144.4444444

Isoelectric point  12.19913393

Charge (pH=7)   1.999749488

Topological polar surface area  1086.03

Aromaticity  0.037037037

Average rotatable bonds  3.407407407

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  36

X logP energy  -7.33399

Hydropathy 



Literature Information


Title  DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence.

DOI  10.1006/cimm.1995.1218,

Publication Year  1995

PubMed ID  7553896,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.