SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04726

Signal sequence   MKFFYLIFSAIFFLADPALVKC

Length  22

Organism  Lutzomyia longipalpis (Sand fly)

UniProt ID  Q5WPZ4,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04726.cif

Structure  SPKB04726.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2585.20334

Aliphatic index  115.4545455

Isoelectric point  8.518677839

Charge (pH=7)   0.935015586

Topological polar surface area  795.43

Aromaticity  0.272727273

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  1.6012

Hydropathy 



Literature Information


Title  Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi.

DOI  10.1242/jeb.01185,

Publication Year  2004

PubMed ID  15371479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.