SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04725

Signal sequence   MKVFFSIFTLVLFQGTLG

Length  18

Organism  Lutzomyia longipalpis (Sand fly)

UniProt ID  Q5WPU9,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04725.cif

Structure  SPKB04725.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2048.51404

Aliphatic index  118.8888889

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  687.82

Aromaticity  0.222222222

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -1.7286

Hydropathy 



Literature Information


Title  Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi.

DOI  10.1242/jeb.01185,

Publication Year  2004

PubMed ID  15371479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.