SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04724

Signal sequence   MMMMTKMFVQIAVVCLLATMAVVSA

Length  25

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  Q5PP12,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04724.cif

Structure  SPKB04724.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2720.53584

Aliphatic index  120.8

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  891.52

Aromaticity  0.04

Average rotatable bonds  3.64

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  38

X logP energy  -3.6291

Hydropathy 



Literature Information


Title  Post-translational modifications of arabinogalactan-peptides of Arabidopsis thaliana. Endoplasmic reticulum and glycosylphosphatidylinositol-anchor signal cleavage sites and hydroxylation of proline.

DOI  10.1074/jbc.M407594200,

Publication Year  2004

PubMed ID  15322080,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.