SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04721

Signal sequence   MKTIPLLFLLFIYFECDG

Length  18

Organism  Anuroctonus phaiodactylus (Mafia scorpion)

UniProt ID  Q5MJP5,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04721.cif

Structure  SPKB04721.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2163.66074

Aliphatic index  130

Isoelectric point  4.184373704

Charge (pH=7)   -1.062914258

Topological polar surface area  690.31

Aromaticity  0.222222222

Average rotatable bonds  3.777777778

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  26

X logP energy  1.2627

Hydropathy 



Literature Information


Title  Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus.

DOI  10.1111/j.1432-1033.2004.04439.x,

Publication Year  2004

PubMed ID  15606762,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.