SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04718

Signal sequence   MHFLVALVLLGQIIGSTLS

Length  19

Organism  Gloydius blomhoffii (Mamushi) (Agkistrodon halys blomhoffi)

UniProt ID  Q5KQS1,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04718.cif

Structure  SPKB04718.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2012.48134

Aliphatic index  179.4736842

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  719.58

Aromaticity  0.052631579

Average rotatable bonds  3.473684211

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -3.3654

Hydropathy 



Literature Information


Title  Properties and cDNA cloning of antihemorrhagic factors in sera of Chinese and Japanese mamushi (Gloydius blomhoffi).

DOI  10.1016/j.toxicon.2007.09.007,

Publication Year  2008

PubMed ID  18037153,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.