SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04717

Signal sequence   MKFSSIILLTLLICSMSIFGNG

Length  22

Organism  Androctonus amoreuxi (African fattail scorpion) (Scorpio amoreuxi)

UniProt ID  Q5K0E0,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04717.cif

Structure  SPKB04717.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2388.96724

Aliphatic index  141.8181818

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  844.68

Aromaticity  0.090909091

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -5.5135

Hydropathy 



Literature Information


Title  Molecular cloning of a novel putative potassium channel-blocking neurotoxin from the venom of the North African scorpion, Androctonus amoreuxi.

DOI  10.1016/j.peptides.2004.12.002,

Publication Year  2005

PubMed ID  15808902,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.