SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04713

Signal sequence   MAATLPVFAVVFFAMVLASSQA

Length  22

Organism  Rhipicephalus bursa (Tick)

UniProt ID  Q5EPH2,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04713.cif

Structure  SPKB04713.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2271.76114

Aliphatic index  115.4545455

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  769.41

Aromaticity  0.136363636

Average rotatable bonds  3.090909091

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  29

X logP energy  -4.2139

Hydropathy 



Literature Information


Title  A carboxypeptidase inhibitor from the tick Rhipicephalus bursa: isolation, cDNA cloning, recombinant expression, and characterization.

DOI  10.1074/jbc.M411086200,

Publication Year  2005

PubMed ID  15561703,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.