SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04711

Signal sequence   MRATAIVLLLALTLATMFS

Length  19

Organism  Homo sapiens (Human)

UniProt ID  Q5DT21,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04711.cif

Structure  SPKB04711.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2036.56224

Aliphatic index  159.4736842

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  729.94

Aromaticity  0.052631579

Average rotatable bonds  3.473684211

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -3.71623

Hydropathy 



Literature Information


Title  SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor.

DOI  10.1038/jid.2008.448,

Publication Year  2009

PubMed ID  19194479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.