General Information
SPKB ID SPKB04708
Signal sequence MLMSTSPSPWLAAAMLCIGLANA
Length 23
Organism Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
UniProt ID Q5B428,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04708.cif
Physicochemical Information
Molecular weight 2349.86484
Aliphatic index 106.5217391
Isoelectric point 5.922539791
Charge (pH=7) -0.063990417
Topological polar surface area 825.74
Aromaticity 0.043478261
Average rotatable bonds 3.086956522
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 33
X logP energy -6.8161
Hydropathy 
Literature Information
Title A seven-transmembrane methyltransferase catalysing N-terminal histidine methylation of lytic polysaccharide monooxygenases.
DOI 10.1038/s41467-023-39875-7,
Publication Year 2023
PubMed ID 37452022,
Patent ID NA,
