General Information
SPKB ID SPKB04706
Signal sequence MTTKIFKRIIVFAVIALSSGNILA
Length 24
Organism Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)
UniProt ID Q59289,
Motif 1..24
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04706.cif
Physicochemical Information
Molecular weight 2607.23644
Aliphatic index 150.4166667
Isoelectric point 11.82305527
Charge (pH=7) 2.99739092
Topological polar surface area 970.57
Aromaticity 0.083333333
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 34
X logP energy -5.74413
Hydropathy
Literature Information
Title Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum.
DOI 10.1128/aem.62.8.2723-2734.1996,
Publication Year 1996
PubMed ID 8702264,
Patent ID NA,