SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04703

Signal sequence   MNYLVVICFALLLMTGVES

Length  19

Organism  Hottentotta judaicus (Black scorpion) (Buthotus judaicus)

UniProt ID  Q56TT9,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04703.cif

Structure  SPKB04703.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2116.61994

Aliphatic index  153.6842105

Isoelectric point  3.84996161

Charge (pH=7)   -1.063065708

Topological polar surface area  728.2

Aromaticity  0.105263158

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -2.2852

Hydropathy 



Literature Information


Title  BjalphaIT: a novel scorpion alpha-toxin selective for insects--unique pharmacological tool.

DOI  10.1016/j.ibmb.2004.11.005,

Publication Year  2005

PubMed ID  15705498,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.