SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04701

Signal sequence   MGRFIFVSFGLLVVFLSLSGTAA

Length  23

Organism  Bothrops jararaca (Jararaca) (Bothrops jajaraca)

UniProt ID  Q56EB0,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04701.cif

Structure  SPKB04701.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2432.94954

Aliphatic index  131.3043478

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.173913043

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -4.45873

Hydropathy 



Literature Information


Title  Identification and characterization of a new member of snake venom thrombin inhibitors from Bothrops insularis using a proteomic approach.

DOI  10.1016/j.toxicon.2007.11.026,

Publication Year  2008

PubMed ID  18221976,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.