SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04694

Signal sequence   MTKTTMHWLAHFQIILLCIWLMCPPSSQA

Length  29

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q4V645,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04694.cif

Structure  SPKB04694.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3402.16984

Aliphatic index  101.0344828

Isoelectric point  8.252149071

Charge (pH=7)   1.055558016

Topological polar surface area  1162.83

Aromaticity  0.103448276

Average rotatable bonds  3.620689655

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  45

X logP energy  -5.1242

Hydropathy 



Literature Information


Title  Identification of the endogenous cysteine-rich peptide trissin, a ligand for an orphan G protein-coupled receptor in Drosophila.

DOI  10.1016/j.bbrc.2011.09.018,

Publication Year  2011

PubMed ID  21939639,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.