SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04692

Signal sequence   MMKLMLFSIIVILFSLIGSIHG

Length  22

Organism  Androctonus australis (Sahara scorpion)

UniProt ID  Q4LCS9,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04692.cif

Structure  SPKB04692.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2464.16704

Aliphatic index  172.7272727

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  789.81

Aromaticity  0.090909091

Average rotatable bonds  3.818181818

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  31

X logP energy  -0.2708

Hydropathy 



Literature Information


Title  A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels.

DOI  10.1042/BJ20041407,

Publication Year  2005

PubMed ID  15656785,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.