SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04691

Signal sequence   MMKLVLFSVIVILFSLIGSIHG

Length  22

Organism  Androctonus australis (Sahara scorpion)

UniProt ID  Q4LCS8,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04691.cif

Structure  SPKB04691.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2418.08024

Aliphatic index  181.3636364

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  789.81

Aromaticity  0.090909091

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -0.758

Hydropathy 



Literature Information


Title  New "Birtoxin analogs" from Androctonus australis venom.

DOI  10.1016/j.bbrc.2005.05.148,

Publication Year  2005

PubMed ID  15963953,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.