SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04689

Signal sequence   MRELDREELNCVGGA

Length  15

Organism  Escherichia coli

UniProt ID  Q46971,

Motif  1..15



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04689.cif

Structure  SPKB04689.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1691.89454

Aliphatic index  78

Isoelectric point  4.147535483

Charge (pH=7)   -2.058225187

Topological polar surface area  786.81

Aromaticity  0

Average rotatable bonds  3.933333333

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  25

X logP energy  -8.62966

Hydropathy 



Literature Information


Title  Characterization of a highly potent antimicrobial peptide microcin N from uropathogenic Escherichia coli.

DOI  10.1093/femsle/fnw095,

Publication Year  2016

PubMed ID  27190283,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.