General Information
SPKB ID SPKB04688
Signal sequence MKTLLLTLVVVTIVCLDLGYT
Length 21
Organism Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
UniProt ID Q45Z11,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04688.cif
Physicochemical Information
Molecular weight 2308.90384
Aliphatic index 185.2380952
Isoelectric point 6.157533513
Charge (pH=7) -0.06468938
Topological polar surface area 809.79
Aromaticity 0.047619048
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -2.5695
Hydropathy
Literature Information
Title Two novel alpha-neurotoxins isolated from the taipan snake, Oxyuranus scutellatus, exhibit reduced affinity for nicotinic acetylcholine receptors in brain and skeletal muscle.
DOI 10.1021/bi9600761,
Publication Year 1996
PubMed ID 8672493,
Patent ID NA,