SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04680

Signal sequence   MSWLLSTMCLVHVCGNIFC

Length  19

Organism  Mesocricetus auratus (Golden hamster)

UniProt ID  Q3YBN2,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04680.cif

Structure  SPKB04680.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2157.66774

Aliphatic index  112.6315789

Isoelectric point  7.17919686

Charge (pH=7)   -0.097030757

Topological polar surface area  735.37

Aromaticity  0.105263158

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -4.2786

Hydropathy 



Literature Information


Title  Purification, cloning and regulation of a novel acid-lipase-like protein of hamster expressed in lacrimal glands and tears during lactation.

DOI  10.1016/j.bbalip.2006.10.002,

Publication Year  2007

PubMed ID  17141562,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.