SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04670

Signal sequence   MRTLWIMAVLLLGVEG

Length  16

Organism  Protobothrops elegans (Elegant pitviper) (Trimeresurus elegans)

UniProt ID  Q2PG81,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04670.cif

Structure  SPKB04670.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.26654

Aliphatic index  164.375

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.6875

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -0.76543

Hydropathy 



Literature Information


Title  Discovery of novel [Arg49]phospholipase A2 isozymes from Protobothrops elegans venom and regional evolution of Crotalinae snake venom phospholipase A2 isozymes in the southwestern islands of Japan and Taiwan.

DOI  10.1016/j.toxicon.2006.06.021,

Publication Year  2006

PubMed ID  16962627,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.