SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04668

Signal sequence   MNSSCKSRVFNIISIIMVSMLILSLGAFANNNKAKA

Length  36

Organism  Staphylococcus aureus (strain NCTC 8325 / PS 47)

UniProt ID  Q2FZL3,

Motif  1..36



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04668.cif

Structure  SPKB04668.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3887.69054

Aliphatic index  113.8888889

Isoelectric point  11.08111025

Charge (pH=7)   3.935121171

Topological polar surface area  1558.61

Aromaticity  0.055555556

Average rotatable bonds  3.75

Number of hydrogen bond donors  55

Number of hydrogen bond acceptors  56

X logP energy  -16.58633

Hydropathy 



Literature Information


Title  Description of staphylococcus serine protease (ssp) operon in Staphylococcus aureus and nonpolar inactivation of sspA-encoded serine protease.

DOI  10.1128/IAI.69.1.159-169.2001,

Publication Year  2001

PubMed ID  11119502,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.