SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04667

Signal sequence   MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKA

Length  36

Organism  Staphylococcus aureus (strain NCTC 8325 / PS 47)

UniProt ID  Q2FXC3,

Motif  1..36



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04667.cif

Structure  SPKB04667.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3743.41494

Aliphatic index  127.2222222

Isoelectric point  9.44154922

Charge (pH=7)   1.000649443

Topological polar surface area  1568.68

Aromaticity  0

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  55

X logP energy  -17.2677

Hydropathy 



Literature Information


Title  Molecular characterization of a novel Staphylococcus aureus serine protease operon.

DOI  10.1128/IAI.69.3.1521-1527.2001,

Publication Year  2001

PubMed ID  11179322,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.