SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04665

Signal sequence   MKTVLILLSILGMACA

Length  16

Organism  Bos taurus (Bovine)

UniProt ID  Q28862,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04665.cif

Structure  SPKB04665.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1677.19514

Aliphatic index  176.875

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  566.3

Aromaticity  0

Average rotatable bonds  3.5625

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  23

X logP energy  -1.7878

Hydropathy 



Literature Information


Title  Phosphorylation of purified bovine bone sialoprotein and osteopontin by protein kinases.

DOI  10.1074/jbc.271.28.16897,

Publication Year  1996

PubMed ID  8663267,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.