SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04661

Signal sequence   MLSRRTLDCCLVMLIVSTTFCQ

Length  22

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  Q27086,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04661.cif

Structure  SPKB04661.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2534.12164

Aliphatic index  115

Isoelectric point  8.04681161

Charge (pH=7)   0.812500013

Topological polar surface area  979.76

Aromaticity  0.045454545

Average rotatable bonds  3.818181818

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  37

X logP energy  -8.94636

Hydropathy 



Literature Information


Title  A limulus intracellular coagulation inhibitor type 2. Purification, characterization, cDNA cloning, and tissue localization.

DOI  10.1074/jbc.270.2.558,

Publication Year  1995

PubMed ID  7822280,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.